Anti-ARHGAP21 antibody (STJA0007941)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human ARHGAP21
General Information
| Short Description | Rabbit polyclonal anti-Rho GTPase-activating protein 21 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ARHGAP21 |
| Gene ID | 57584 |
| Uniprot ID | RHG21_HUMAN |
| Immunogen | Synthesized peptide derived from human ARHGAP21 |
| Specificity | This antibody detects endogenous levels of ARHGAP21 at Human, Mouse |
Additional Info
| Post Translational Modifications | Sumoylated with SUMO2 and SUMO3 in proliferating lymphocytes. |
| Function | Functions as a GTPase-activating protein (GAP) for RHOA and CDC42. Downstream partner of ARF1 which may control Golgi apparatus structure and function. Also required for CTNNA1 recruitment to adherens junctions. |
| Protein Name | Rho Gtpase-Activating Protein 21Rho Gtpase-Activating Protein 10Rho-Type Gtpase-Activating Protein 21 |
| Database Links | Reactome: R-HSA-8980692Reactome: R-HSA-9013026Reactome: R-HSA-9013106Reactome: R-HSA-9013148Reactome: R-HSA-9013149Reactome: R-HSA-9013404Reactome: R-HSA-9013405Reactome: R-HSA-9013406Reactome: R-HSA-9013408Reactome: R-HSA-9013409Reactome: R-HSA-9013423Reactome: R-HSA-9035034Reactome: R-HSA-9696264 |
| Cellular Localisation | Golgi Apparatus MembranePeripheral Membrane ProteinCell JunctionCytoplasmic Vesicle MembraneCytoplasmCytoskeletonLocalization To The Golgi Is Dependent On Interaction With Gtp-Bound Arf1 |
| Alternative Antibody Names | Anti-Rho Gtpase-Activating Protein 21 antibodyAnti-Rho Gtpase-Activating Protein 10 antibodyAnti-Rho-Type Gtpase-Activating Protein 21 antibodyAnti-ARHGAP21 antibodyAnti-ARHGAP10 antibodyAnti-KIAA1424 antibody |
Information sourced from Uniprot.org