| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Rho GTPase-activating protein 21 is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ARHGAP21 |
| Gene ID: | 57584 |
| Uniprot ID: | RHG21_HUMAN |
| Specificity: | This antibody detects endogenous levels of ARHGAP21 at Human, Mouse |
| Immunogen: | Synthesized peptide derived from human ARHGAP21 |
| Post Translational Modifications | Sumoylated with SUMO2 and SUMO3 in proliferating lymphocytes. |
| Function | Functions as a GTPase-activating protein (GAP) for RHOA and CDC42. Downstream partner of ARF1 which may control Golgi apparatus structure and function. Also required for CTNNA1 recruitment to adherens junctions. |
| Protein Name | Rho Gtpase-Activating Protein 21Rho Gtpase-Activating Protein 10Rho-Type Gtpase-Activating Protein 21 |
| Database Links | Reactome: R-HSA-8980692Reactome: R-HSA-9013026Reactome: R-HSA-9013106Reactome: R-HSA-9013148Reactome: R-HSA-9013149Reactome: R-HSA-9013404Reactome: R-HSA-9013405Reactome: R-HSA-9013406Reactome: R-HSA-9013408Reactome: R-HSA-9013409Reactome: R-HSA-9013423Reactome: R-HSA-9035034Reactome: R-HSA-9696264 |
| Cellular Localisation | Golgi Apparatus MembranePeripheral Membrane ProteinCell JunctionCytoplasmic Vesicle MembraneCytoplasmCytoskeletonLocalization To The Golgi Is Dependent On Interaction With Gtp-Bound Arf1 |
| Alternative Antibody Names | Anti-Rho Gtpase-Activating Protein 21 antibodyAnti-Rho Gtpase-Activating Protein 10 antibodyAnti-Rho-Type Gtpase-Activating Protein 21 antibodyAnti-ARHGAP21 antibodyAnti-ARHGAP10 antibodyAnti-KIAA1424 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance