Anti-ARHGAP1 antibody (210-439) (STJ22672)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ARHGAP1 (210-439) antibody for use in WB, IP and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IP/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ARHGAP1 |
| Gene ID | 392 |
| Uniprot ID | RHG01_HUMAN |
| Immunogen Region | 210-439 |
| Immunogen Sequence | VLKYDDFLKSTQKSPATAPK PMPPRPPLPNQQFGVSLQHL QEKNPEQEPIPIVLRETVAY LQAHALTTEGIFRRSANTQV VREVQQKYNMGLPVDFDQYN ELHLPAVILKTFLRELPEPL LTFDLYPHVVGFLNIDESQR VPATLQVLQTLPEENYQVLR FLTAFLVQISAHSDQNKMTN TNLAVVFGPNLLWAKDAAIT LKAINPINTFTKFLLDHQGE LFPSPDPSGL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 210-439 of human ARHGAP1 (NP_004299.1). |
Additional Info
| Tissue Specificity | Ubiquitous. |
| Function | GTPase activator for the Rho, Rac and Cdc42 proteins, converting them to the putatively inactive GDP-bound state. Cdc42 seems to be the preferred substrate. |
| Protein Name | Rho Gtpase-Activating Protein 1Cdc42 Gtpase-Activating ProteinGtpase-Activating Protein RhogapRho-Related Small Gtpase Protein ActivatorRho-Type Gtpase-Activating Protein 1P50-Rhogap |
| Database Links | Reactome: R-HSA-8980692Reactome: R-HSA-9013026Reactome: R-HSA-9013106Reactome: R-HSA-9013148Reactome: R-HSA-9013149Reactome: R-HSA-9013404Reactome: R-HSA-9013405Reactome: R-HSA-9013406Reactome: R-HSA-9013408Reactome: R-HSA-9013409Reactome: R-HSA-9013423Reactome: R-HSA-9035034Reactome: R-HSA-9696270 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Rho Gtpase-Activating Protein 1 antibodyAnti-Cdc42 Gtpase-Activating Protein antibodyAnti-Gtpase-Activating Protein Rhogap antibodyAnti-Rho-Related Small Gtpase Protein Activator antibodyAnti-Rho-Type Gtpase-Activating Protein 1 antibodyAnti-P50-Rhogap antibodyAnti-ARHGAP1 antibodyAnti-CDC42GAP antibodyAnti-RHOGAP1 antibody |
Information sourced from Uniprot.org