Anti-AREG antibody (20-252) (STJ114553)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal AREG (20-252) antibody for use in IF, ICC and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AREG |
| Gene ID | 374 |
| Uniprot ID | AREG_HUMAN |
| Immunogen Region | 20-252 |
| Immunogen Sequence | SGHYAAGLDLNDTYSGKREP FSGDHSADGFEVTSRSEMSS GSEISPVSEMPSSSEPSSGA DYDYSEEYDNEPQIPGYIVD DSVRVEQVVKPPQNKTESEN TSDKPKRKKKGGKNGKNRRN RKKKNPCNAEFQNFCIHGEC KYIEHLEAVTCKCQQEYFGE RCGEKSMKTHSMIDSSLSKI ALAAIAAFMSAVILTAVAVI TVQLRRQYVRKYEGEAEERK KLRQENGNVHAIA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 20-252 of human AREG (NP_001648.1). |
Additional Info
| Function | Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts. |
| Protein Name | AmphiregulinArColorectum Cell-Derived Growth FactorCrdgf |
| Database Links | Reactome: R-HSA-1257604Reactome: R-HSA-177929Reactome: R-HSA-179812Reactome: R-HSA-180292Reactome: R-HSA-180336Reactome: R-HSA-182971Reactome: R-HSA-204005Reactome: R-HSA-212718Reactome: R-HSA-2219530Reactome: R-HSA-5638303Reactome: R-HSA-5673001Reactome: R-HSA-5694530Reactome: R-HSA-6811558Reactome: R-HSA-8856825Reactome: R-HSA-8856828Reactome: R-HSA-9009391Reactome: R-HSA-9634638Reactome: R-HSA-9818030 |
| Cellular Localisation | MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Amphiregulin antibodyAnti-Ar antibodyAnti-Colorectum Cell-Derived Growth Factor antibodyAnti-Crdgf antibodyAnti-AREG antibodyAnti-AREGB antibodyAnti-SDGF antibody |
Information sourced from Uniprot.org