Anti-ARAP3 antibody (STJA0008431)

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STJA0008431
$67.62 - $360.18
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Short Description :Rabbit polyclonal anti-Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB
Host:Rabbit
Reactivity:Human/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-2000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:ARAP3
Gene ID:64411
Uniprot ID:ARAP3_HUMAN
Immunogen:Synthesized peptide derived from human ARAP3
Specificity:This antibody detects endogenous levels of ARAP3 at Human, Mouse
Function Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Acts on ARF6, RAC1, RHOA and CDC42. Plays a role in the internalization of anthrax toxin.
Protein Name Arf-Gap With Rho-Gap Domain - Ank Repeat And Ph Domain-Containing Protein 3
Centaurin-Delta-3
Cnt-D3
Database Links Reactome: R-HSA-8980692
Reactome: R-HSA-9013148
Reactome: R-HSA-9013149
Reactome: R-HSA-9013423
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Membrane
Peripheral Membrane Protein
Cell Projection
Lamellipodium
Ruffle
Cytoplasmic
And Associated With F-Actin-Rich Membrane Ruffles And Lamellipodia
Alternative Antibody Names Anti-Arf-Gap With Rho-Gap Domain - Ank Repeat And Ph Domain-Containing Protein 3 antibody
Anti-Centaurin-Delta-3 antibody
Anti-Cnt-D3 antibody
Anti-ARAP3 antibody
Anti-CENTD3 antibody

Information sourced from Uniprot.org

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