Anti-ARAF antibody (N-Term) [M289] (STJA0005557)

SKU:
STJA0005557-100

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Host: Mouse
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-A-Raf (N-Term) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: M289
Conjugation: Unconjugated
Isotype: IgG1
Formulation: PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol
Purification: Antigen Affinity Purified
Dilution Range: WB 1:1000
IHC
ICC
IP
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ARAF
Gene ID: 369
Uniprot ID: ARAF_HUMAN
Immunogen Region: N-Term
Specificity: This antibody detects a 68 kDa* protein corresponding to the molecular mass of A-Raf on SDS-PAGE immunoblots of human SKN-SH and Jurkat cells.
Immunogen: Clone (M289) was generated from a sequence corresponding to amino acids in the N-terminal region of human A-Raf. This A-Raf sequence has high homology to rat and mouse A-Raf.
Function Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May also regulate the TOR signaling cascade. Phosphorylates PFKFB2. Isoform 2: Serves as a positive regulator of myogenic differentiation by inducing cell cycle arrest, the expression of myogenin and other muscle-specific proteins, and myotube formation.
Protein Name Serine/Threonine-Protein Kinase A-Raf
Proto-Oncogene A-Raf
Proto-Oncogene A-Raf-1
Proto-Oncogene Pks
Database Links Reactome: R-HSA-5673000
Reactome: R-HSA-5674135
Reactome: R-HSA-5675221
Reactome: R-HSA-6802946
Reactome: R-HSA-6802948
Reactome: R-HSA-6802952
Reactome: R-HSA-6802955
Reactome: R-HSA-9649948
Reactome: R-HSA-9656223
Reactome: R-HSA-9726840
Reactome: R-HSA-9726842
Alternative Antibody Names Anti-Serine/Threonine-Protein Kinase A-Raf antibody
Anti-Proto-Oncogene A-Raf antibody
Anti-Proto-Oncogene A-Raf-1 antibody
Anti-Proto-Oncogene Pks antibody
Anti-ARAF antibody
Anti-ARAF1 antibody
Anti-PKS antibody
Anti-PKS2 antibody

Information sourced from Uniprot.org

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