Anti-Aquaporin 3 antibody [SM5102] (STJA0005102)

Name: Anti-Aquaporin 3 antibody [SM5102] (STJA0005102)
SKU: STJA0005102
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityMonoclonal

HostMouse

ConjugationUnconjugated

IsotypeIgG

ImmunogenRecombinant protein corresponding to Mouse Aquaporin 3

STJA0005102

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Short Description	Mouse monoclonal anti-Aquaporin 3 for use in IHC and IF in Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	IHC/IF
Host	Mouse
Reactivity	Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Monoclonal
Clone ID	SM5102
Isotype	IgG
Conjugation	Unconjugated
Purification	Affinity purification
Dilution Range	IHC/IF (M, R) 1:1000-1:2000
Formulation	PBS with 0.02% sodium azide, 100 Mu g/ml BSA and 50% glycerol.
Storage Instruction	Store at-20C for up to one year, and avoid repeated freeze-thaw cycles.

Gene Symbol	Aqp3
Gene ID	11828
Uniprot ID	AQP3_MOUSE
Immunogen	Recombinant protein corresponding to Mouse Aquaporin 3

Function	Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient. Could also be permeable to urea. Also participates in cell permeability to H2O2 and H2O2-mediated signaling. In skin, transports glycerol to the epidermis and stratum corneum, where it maintains hydration, elasticity, and supports lipid biosynthesis for barrier repair. In kidney, contributes to the reabsorption of water, helping the body maintain proper fluid balance.
Protein Name	Aquaporin-3 Aqp-3 Aquaglyceroporin-3
Database Links	Reactome: R-MMU-432040 Reactome: -MMU-432047
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein Basolateral Cell Membrane
Alternative Antibody Names	Anti-Aquaporin-3 antibody Anti-Aqp-3 antibody Anti-Aquaglyceroporin-3 antibody Anti-Aqp3 antibody

Information sourced from Uniprot.org