• Immunohistochemistry of mouse liver with Anti-AQR primary antibody (STJ500150) at 1:50 dilution in Buffer. Section was treated with DAB and Haematoxylin stain. Magnification is at 40X.

Anti-AQR antibody (1250-1300) (STJ500150)

SKU:
STJ500150-100

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Host: Rabbit
Applications: ELISA/IHC/IP/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-AQR (1250-1300) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.57-0.60 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:250
IHC: 1:50-1:250
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: AQR
Gene ID: 9716
Uniprot ID: AQR_HUMAN
Immunogen Region: 1250-1300
Immunogen: Synthetic peptide taken within amino acid region 1250-1300 on human RNA helicase aquarius protein.
Function Involved in pre-mRNA splicing as component of the spliceosome. Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. Has ATP-dependent RNA helicase activity and can unwind double-stranded RNA molecules with a 3' overhang (in vitro).
Protein Name Rna Helicase Aquarius
Intron-Binding Protein Of 160 Kda
Ibp160
Database Links Reactome: R-HSA-6781823
Reactome: R-HSA-6781827
Reactome: R-HSA-6782135
Reactome: R-HSA-6782210
Reactome: R-HSA-72163
Cellular Localisation Nucleus
Nucleoplasm
Localizes To Speckle-Like Regions Of The Nucleoplasm
Alternative Antibody Names Anti-Rna Helicase Aquarius antibody
Anti-Intron-Binding Protein Of 160 Kda antibody
Anti-Ibp160 antibody
Anti-AQR antibody
Anti-KIAA0560 antibody

Information sourced from Uniprot.org

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