Anti-AQP3 antibody (200-250) {Biotin} (STJ500130)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationBiotin
IsotypeIgG
ImmunogenSynthetic peptide taken within amino acid region 200-250 on rat Aquaporin 3 protein.
General Information
| Short Description | Rabbit polyclonal antibody anti-AQP3 (200-250) is suitable for use in ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Applications | ELISA/ICC/IF/IHC/IP/WB |
| Host | Rabbit |
| Reactivity | Bovine/Human/Mouse/Rat/Sheep |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Biotin |
| Concentration | 0.50-0.57 ยตg/ยตl |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:500ELISA: 1:10, 000IP: 1:200IHC: 1:100ICC: 1:100IF: 1:100 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | Aqp3 |
| Gene ID | 65133 |
| Uniprot ID | AQP3_RAT |
| Immunogen | Synthetic peptide taken within amino acid region 200-250 on rat Aquaporin 3 protein. |
| Immunogen Region | 200-250 |
Additional Info
| Tissue Specificity | Detected in kidney medulla and papilla, in collecting duct cells. Detected in colon. |
| Function | Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient. Could also be permeable to urea. Also participates in cell permeability to H2O2 and H2O2-mediated signaling. In skin, transports glycerol to the epidermis and stratum corneum, where it maintains hydration, elasticity, and supports lipid biosynthesis for barrier repair. In kidney, contributes to the reabsorption of water, helping the body maintain proper fluid balance. |
| Protein Name | Aquaporin-3Aqp-331.4 Kda Water Channel ProteinAquaglyceroporin-3 |
| Database Links | Reactome: R-RNO-432040Reactome: -RNO-432047 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinBasolateral Cell Membrane |
| Alternative Antibody Names | Anti-Aquaporin-3 antibodyAnti-Aqp-3 antibodyAnti-31.4 Kda Water Channel Protein antibodyAnti-Aquaglyceroporin-3 antibodyAnti-Aqp3 antibody |
Information sourced from Uniprot.org