Anti-APXL antibody (C-Term) (STJ73285)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-APXL (C-Term) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/IHC |
| Host | Goat |
| Reactivity | Human/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:32000.IHC: In paraffin embedded Human Kidney shows cytoplasm staining in PCT exclusively. Recommended concentration, 4-6µg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | SHROOM2 |
| Gene ID | 357 |
| Uniprot ID | SHRM2_HUMAN |
| Accession Number | NP_001640 |
| Immunogen Region | C-Term |
| Immunogen Sequence | KCLLDSLQPERGK |
Additional Info
| Function | May be involved in endothelial cell morphology changes during cell spreading. In the retinal pigment epithelium, may regulate the biogenesis of melanosomes and promote their association with the apical cell surface by inducing gamma-tubulin redistribution. |
| Protein Name | Protein Shroom2Apical-Like ProteinProtein Apxl |
| Cellular Localisation | Apical Cell MembraneCell JunctionTight JunctionCytoplasmCytoskeletonAssociates With Cortical F-Actin |
| Alternative Antibody Names | Anti-Protein Shroom2 antibodyAnti-Apical-Like Protein antibodyAnti-Protein Apxl antibodyAnti-SHROOM2 antibodyAnti-APXL antibody |
Information sourced from Uniprot.org