| Host: | Goat |
| Applications: | Pep-ELISA/WB/FC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-APOLD1/VERGE (C-Term) is suitable for use in ELISA, Western Blot and Flow Cytometry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:2000.WB: Approx. 35kDa band observed in lysates of cell lines A431, Jurkat and U251 (calculated MW of 30.5kDa according to Human NP_001123887.1).This molecular weight is routinely observed by ot |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | APOLD1 |
| Gene ID: | 81575 |
| Uniprot ID: | APLD1_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_110444.1 |
| Immunogen Sequence: | KSSRGHDLKISADQ |
| Function | Is a modulator of endothelial barrier permeability, required for proper organization of endothelial cell-cell junctions and cytoskeleton. It also plays a role in the modulation of secretory autophagy. May affect blood-brain barrier permeability. |
| Protein Name | Apolipoprotein L Domain-Containing Protein 1Vascular Early Response Gene Protein |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCell JunctionCytoplasmic VesicleSecretory VesicleLocalized To Weibel-Palade BodiesSecretory Granules Characteristic Of Vascular Endothelial Cells |
| Alternative Antibody Names | Anti-Apolipoprotein L Domain-Containing Protein 1 antibodyAnti-Vascular Early Response Gene Protein antibodyAnti-APOLD1 antibodyAnti-VERGE antibody |
Information sourced from Uniprot.org