Anti-APOH antibody (21-345) (STJ22654)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal APOH (21-345) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | APOH |
| Gene ID | 350 |
| Uniprot ID | APOH_HUMAN |
| Immunogen Region | 21-345 |
| Immunogen Sequence | RTCPKPDDLPFSTVVPLKTF YEPGEEITYSCKPGYVSRGG MRKFICPLTGLWPINTLKCT PRVCPFAGILENGAVRYTTF EYPNTISFSCNTGFYLNGAD SAKCTEEGKWSPELPVCAPI ICPPPSIPTFATLRVYKPSA GNNSLYRDTAVFECLPQHAM FGNDTITCTTHGNWTKLPEC REVKCPFPSRPDNGFVNYPA KPTLYYKDKATFGCHDGYSL DGPEEIECTKLGNWSAMPS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 21-345 of human APOH (NP_000033.2). |
Additional Info
| Tissue Specificity | Expressed by the liver and secreted in plasma. |
| Post Translational Modifications | N- and O-glycosylated. PubMed:6587378 also reports glycosylation on 'Asn-188' for their allele. |
| Function | Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells. |
| Protein Name | Beta-2-Glycoprotein 1Apc InhibitorActivated Protein C-Binding ProteinAnticardiolipin CofactorApolipoprotein HApo-HBeta-2-Glycoprotein IB2gpiBeta(2gpi |
| Database Links | Reactome: R-HSA-114608 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Beta-2-Glycoprotein 1 antibodyAnti-Apc Inhibitor antibodyAnti-Activated Protein C-Binding Protein antibodyAnti-Anticardiolipin Cofactor antibodyAnti-Apolipoprotein H antibodyAnti-Apo-H antibodyAnti-Beta-2-Glycoprotein I antibodyAnti-B2gpi antibodyAnti-Beta(2gpi antibodyAnti-APOH antibodyAnti-B2G1 antibody |
Information sourced from Uniprot.org