Anti-APOH antibody (145-157) (STJ72692)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-APOH (145-157) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:1000.WB: Approx 50kDa band observed in Human Liver, Kidney and Placenta lysates (calculated MW of 38.3kDa according to NP_000033.2). The observed molecular weight corresponds to earlier findings |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | APOH |
| Gene ID | 350 |
| Uniprot ID | APOH_HUMAN |
| Accession Number | NP_000033.2 |
| Immunogen Region | 145-157 |
| Immunogen Sequence | PSIPTFATLRVYK |
Additional Info
| Post Translational Modifications | N- and O-glycosylated. PubMed:6587378 also reports glycosylation on 'Asn-188' for their allele. |
| Function | Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells. |
| Protein Name | Beta-2-Glycoprotein 1Apc InhibitorActivated Protein C-Binding ProteinAnticardiolipin CofactorApolipoprotein HApo-HBeta-2-Glycoprotein IB2gpiBeta(2gpi |
| Database Links | Reactome: R-HSA-114608 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Beta-2-Glycoprotein 1 antibodyAnti-Apc Inhibitor antibodyAnti-Activated Protein C-Binding Protein antibodyAnti-Anticardiolipin Cofactor antibodyAnti-Apolipoprotein H antibodyAnti-Apo-H antibodyAnti-Beta-2-Glycoprotein I antibodyAnti-B2gpi antibodyAnti-Beta(2gpi antibodyAnti-APOH antibodyAnti-B2G1 antibody |
Information sourced from Uniprot.org