| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Apolipoprotein C-II (1-50 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC-P 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | APOC2 |
| Gene ID: | 344 |
| Uniprot ID: | APOC2_HUMAN |
| Immunogen Region: | 1-50 aa |
| Specificity: | This antibody detects endogenous levels of human APOC2 |
| Immunogen: | Synthesized peptide derived from the human APOC2 at the amino acid range 1-50 |
| Post Translational Modifications | Proapolipoprotein C-II is synthesized as a sialic acid containing glycoprotein which is subsequently desialylated prior to its proteolytic processing. Proapolipoprotein C-II, the major form found in plasma undergoes proteolytic cleavage of its N-terminal hexapeptide to generate apolipoprotein C-II, which occurs as the minor form in plasma. |
| Function | Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase. Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase. In normolipidemic individuals, it is mainly distributed in the HDL, whereas in hypertriglyceridemic individuals, predominantly found in the VLDL and LDL. |
| Protein Name | Apolipoprotein C-IiApo-CiiApoc-IiApolipoprotein C2 Cleaved Into - Proapolipoprotein C-IiProapoc-Ii |
| Database Links | Reactome: R-HSA-8963888Reactome: R-HSA-8963889Reactome: R-HSA-8963901Reactome: R-HSA-8964058Reactome: R-HSA-9029569Reactome: R-HSA-975634 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Apolipoprotein C-Ii antibodyAnti-Apo-Cii antibodyAnti-Apoc-Ii antibodyAnti-Apolipoprotein C2 Cleaved Into - Proapolipoprotein C-Ii antibodyAnti-Proapoc-Ii antibodyAnti-APOC2 antibodyAnti-APC2 antibody |
Information sourced from Uniprot.org
