• Immunohistochemistry analysis of paraffin-embedded human lung using APOC1 antibody (STJ27596) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.

Anti-APOC1 antibody (1-83) (STJ27596)

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STJ27596

£169.50 - £449.50
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Host: Rabbit
Applications: IHC
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-APOC1 (1-83) is suitable for use in Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: IHC-P 1:50-1:100
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: APOC1
Gene ID: 341
Uniprot ID: APOC1_HUMAN
Immunogen Region: 1-83
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-83 of human APOC1 (NP_001636.1).
Immunogen Sequence: MRLFLSLPVLVVVLSIVLEG PAPAQGTPDVSSALDKLKEF GNTLEDKARELISRIKQSEL SAKMREWFSETFQKVKEKLK IDS
Tissue Specificity Synthesized mainly in liver and to a minor degree in intestine. Also found in the lung and spleen.
Function Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL. Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP). Binds free fatty acids and reduces their intracellular esterification. Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein.
Protein Name Apolipoprotein C-I
Apo-Ci
Apoc-I
Apolipoprotein C1 Cleaved Into - Truncated Apolipoprotein C-I
Database Links Reactome: R-HSA-8866423
Reactome: R-HSA-8964046
Reactome: R-HSA-9029569
Cellular Localisation Secreted
Alternative Antibody Names Anti-Apolipoprotein C-I antibody
Anti-Apo-Ci antibody
Anti-Apoc-I antibody
Anti-Apolipoprotein C1 Cleaved Into - Truncated Apolipoprotein C-I antibody
Anti-APOC1 antibody

Information sourced from Uniprot.org

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