| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-APOBEC2 (1-224) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
APOBEC2 |
| Gene ID: |
10930 |
| Uniprot ID: |
ABEC2_HUMAN |
| Immunogen Region: |
1-224 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-224 of human APOBEC2 (NP_006780.1). |
| Immunogen Sequence: |
MAQKEEAAVATEAASQNGED LENLDDPEKLKELIELPPFE IVTGERLPANFFKFQFRNVE YSSGRNKTFLCYVVEAQGKG GQVQASRGYLEDEHAAAHAE EAFFNTILPAFDPALRYNVT WYVSSSPCAACADRIIKTLS KTKNLRLLILVGRLFMWEEP EIQAALKKLKEAGCKLRIMK PQDFEYVWQNFVEQEEGESK AFQPWEDIQENFLYYEEKLA DILK |
| Tissue Specificity | Expressed exclusively in heart and skeletal muscle. |
| Function | Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation. |
| Protein Name | C->U-Editing Enzyme Apobec-2Mrna(Cytosine(6666 Deaminase 2 |
| Database Links | Reactome: R-HSA-72200Reactome: R-HSA-75094 |
| Alternative Antibody Names | Anti-C->U-Editing Enzyme Apobec-2 antibodyAnti-Mrna(Cytosine(6666 Deaminase 2 antibodyAnti-APOBEC2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
