| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-APOBEC1 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx. 28kDa band observed in Mouse Spleen lysates (calculated MW of 28.2kDa according to Human NP_001635.2 and 27.5kDa acccording to Mouse NP_112436.1). Recommended concentration: 1- |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | APOBEC1 |
| Gene ID: | 339 |
| Uniprot ID: | ABEC1_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_001635.2 |
| Immunogen Sequence: | DVFYDPRELRKEAC |
| Function | Cytidine deaminase catalyzing the cytidine to uridine postranscriptional editing of a variety of mRNAs. Form complexes with cofactors that confer differential editing activity and selectivity. Responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the apolipoprotein B mRNA. Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation. |
| Protein Name | C->U-Editing Enzyme Apobec-1Apolipoprotein B Mrna-Editing Enzyme Catalytic Subunit 1Apo1Apobec-1Apolipoprotein B Mrna-Editing Enzyme 1HeprMrna(Cytosine(6666 Deaminase 1 |
| Database Links | Reactome: R-HSA-72200Reactome: R-HSA-75094 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-C->U-Editing Enzyme Apobec-1 antibodyAnti-Apolipoprotein B Mrna-Editing Enzyme Catalytic Subunit 1 antibodyAnti-Apo1 antibodyAnti-Apobec-1 antibodyAnti-Apolipoprotein B Mrna-Editing Enzyme 1 antibodyAnti-Hepr antibodyAnti-Mrna(Cytosine(6666 Deaminase 1 antibodyAnti-APOBEC1 antibody |
Information sourced from Uniprot.org