| Host: |
Goat |
| Applications: |
Pep-ELISA/WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-APOBEC1 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-1-3µg/mlELISA-antibody detection limit dilution 1:32000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
APOBEC1 |
| Gene ID: |
339 |
| Uniprot ID: |
ABEC1_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_001635.2 |
| Immunogen Sequence: |
DVFYDPRELRKEAC |
| Function | Cytidine deaminase catalyzing the cytidine to uridine postranscriptional editing of a variety of mRNAs. Form complexes with cofactors that confer differential editing activity and selectivity. Responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the apolipoprotein B mRNA. Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation. |
| Protein Name | C->U-Editing Enzyme Apobec-1Apolipoprotein B Mrna-Editing Enzyme Catalytic Subunit 1Apo1Apobec-1Apolipoprotein B Mrna-Editing Enzyme 1HeprMrna(Cytosine(6666 Deaminase 1 |
| Database Links | Reactome: R-HSA-72200Reactome: R-HSA-75094 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-C->U-Editing Enzyme Apobec-1 antibodyAnti-Apolipoprotein B Mrna-Editing Enzyme Catalytic Subunit 1 antibodyAnti-Apo1 antibodyAnti-Apobec-1 antibodyAnti-Apolipoprotein B Mrna-Editing Enzyme 1 antibodyAnti-Hepr antibodyAnti-Mrna(Cytosine(6666 Deaminase 1 antibodyAnti-APOBEC1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
