Anti-APOB antibody (STJA0010126)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human APOB
General Information
| Short Description | Rabbit polyclonal anti-Apolipoprotein B-100 for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | APOB |
| Gene ID | 338 |
| Uniprot ID | APOB_HUMAN |
| Immunogen | Synthesized peptide derived from human APOB |
| Specificity | This antibody detects endogenous levels of Human APOB |
Additional Info
| Post Translational Modifications | Palmitoylated.structural requirement for proper assembly of the hydrophobic core of the lipoprotein particle. |
| Function | Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. |
| Protein Name | Apolipoprotein B-100Apo B-100 Cleaved Into - Apolipoprotein B-48Apo B-48 |
| Database Links | Reactome: R-HSA-202733Reactome: R-HSA-3000471Reactome: R-HSA-3000480Reactome: R-HSA-3000484Reactome: R-HSA-3000497Reactome: R-HSA-381426Reactome: R-HSA-432142Reactome: R-HSA-5686938Reactome: R-HSA-8856825Reactome: R-HSA-8856828Reactome: R-HSA-8866423Reactome: R-HSA-8957275Reactome: R-HSA-8963888Reactome: R-HSA-8963901Reactome: R-HSA-8964026Reactome: R-HSA-8964038Reactome: R-HSA-8964041Reactome: R-HSA-8964046Reactome: R-HSA-9707616Reactome: R-HSA-975634 |
| Cellular Localisation | CytoplasmSecretedLipid Droplet |
| Alternative Antibody Names | Anti-Apolipoprotein B-100 antibodyAnti-Apo B-100 Cleaved Into - Apolipoprotein B-48 antibodyAnti-Apo B-48 antibodyAnti-APOB antibody |
Information sourced from Uniprot.org