Anti-APOA5 antibody [4H8H8E2 (c)] (STJ97837)

SKU:
STJ97837

Current Stock:
Host: Mouse
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Apolipoprotein A-V is suitable for use in ELISA research applications.
Clonality: Monoclonal
Clone ID: 4H8H8E2 (c)
Conjugation: Unconjugated
Isotype: IgG1
Formulation: Liquid in PBS containing 0.03% Sodium Azide.
Purification: Affinity purification
Concentration: 1 mg/mL
Dilution Range: ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: APOA5
Gene ID: 116519
Uniprot ID: APOA5_HUMAN
Specificity: ApoA-V (bd) Monoclonal Antibody detects endogenous levels of ApoA-V (bd) protein.
Immunogen: Purified recombinant fragment of human ApoA-V expressed in E. Coli.
Post Translational Modifications Phosphorylated by FAM20C in the extracellular medium.
Function Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. May also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and an inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate). Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages. Binds heparin.
Protein Name Apolipoprotein A-V
Apo-Av
Apoa-V
Apolipoprotein A5
Regeneration-Associated Protein 3
Database Links Reactome: R-HSA-1989781
Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Reactome: R-HSA-8963889
Reactome: R-HSA-8963901
Cellular Localisation Secreted
Early Endosome
Late Endosome
Golgi Apparatus
Trans-Golgi Network
In The Presence Of Sorl1
Internalized To Early Endosomes
Sorted In A Retrograde Fashion To Late Endosomes
From Which A Portion Is Sent To Lysosomes And Degradation
Another Portion Is Sorted To The Trans-Golgi Network
Alternative Antibody Names Anti-Apolipoprotein A-V antibody
Anti-Apo-Av antibody
Anti-Apoa-V antibody
Anti-Apolipoprotein A5 antibody
Anti-Regeneration-Associated Protein 3 antibody
Anti-APOA5 antibody
Anti-RAP3 antibody
Anti-UNQ411 antibody
Anti-PRO773 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance