Anti-APOA4 antibody (21-396) [S5250RM] (STJ11105250)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Apolipoprotein A-Iv (21-396) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S5250RM |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | APOA4 |
| Gene ID | 337 |
| Uniprot ID | APOA4_HUMAN |
| Immunogen Region | 21-396 |
| Immunogen Sequence | EVSADQVATVMWDYFSQLSN NAKEAVEHLQKSELTQQLNA LFQDKLGEVNTYAGDLQKKL VPFATELHERLAKDSEKLKE EIGKELEELRARLLPHANEV SQKIGDNLRELQQRLEPYAD QLRTQVSTQAEQLRRQLTPY AQRMERVLRENADSLQASLR PHADELKAKIDQNVEELKGR LTPYADEFKVKIDQTVEELR RSLAPYAQDTQEKLNHQLEG LTFQMKKNAEELKARISAS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 21-396 of human APOA4 (NP_000473.2). |
Additional Info
| Tissue Specificity | Synthesized primarily in the intestine and secreted in plasma. |
| Post Translational Modifications | Phosphorylation sites are present in the extracellular medium. |
| Function | May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II.potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons. |
| Protein Name | Apolipoprotein A-IvApo-AivApoa-IvApolipoprotein A4 |
| Database Links | Reactome: R-HSA-8963888Reactome: R-HSA-8963889Reactome: R-HSA-8963901Reactome: R-HSA-975634Reactome: R-HSA-977225 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Apolipoprotein A-Iv antibodyAnti-Apo-Aiv antibodyAnti-Apoa-Iv antibodyAnti-Apolipoprotein A4 antibodyAnti-APOA4 antibody |
Information sourced from Uniprot.org