Anti-ApoA antibody [R04-2L8] (STJA0037306)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human ApoA
General Information
| Short Description | Rabbit monoclonal anti-ApoA for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R04-2L8 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | LPA |
| Gene ID | 4018 |
| Uniprot ID | APOA_HUMAN |
| Immunogen | A synthesized peptide derived from human ApoA |
Additional Info
| Post Translational Modifications | N- and O-glycosylated. The N-glycans are complex biantennary structures present in either a mono- or disialylated state. The O-glycans are mostly (80%) represented by the monosialylated core type I structure, NeuNAcalpha2-3Galbeta1-3GalNAc, with smaller amounts of disialylated and non-sialylated O-glycans also detected. |
| Function | Apo(a) is the main constituent of lipoprotein(a) (Lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1. Lp(a) may be a ligand for megalin/Gp 330. |
| Protein Name | Apolipoprotein(AApo(ALp(A |
| Database Links | Reactome: R-HSA-8964041 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Apolipoprotein(A antibodyAnti-Apo(A antibodyAnti-Lp(A antibodyAnti-LPA antibody |
Information sourced from Uniprot.org