Anti-APLP2 antibody (241-290 aa) (STJ91633)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human APLP2 at the amino acid range 241-290
General Information
| Short Description | Rabbit polyclonal anti-Amyloid beta precursor like protein 2 precursor-like protein 2 (241-290 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | APLP2 |
| Gene ID | 334 |
| Uniprot ID | APLP2_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human APLP2 at the amino acid range 241-290 |
| Immunogen Region | 241-290 aa |
| Specificity | APLP-2 Polyclonal Antibody detects endogenous levels of APLP-2 protein. |
Additional Info
| Post Translational Modifications | The BPTI/Kunitz inhibitor domain is O-glycosylated. |
| Function | May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts. |
| Protein Name | Amyloid Beta Precursor Like Protein 2ApphAmyloid BetaA4 Precursor-Like Protein 2Amyloid Protein HomologAmyloid-Like Protein 2Aplp-2Cdei Box-Binding ProteinCdebpSperm Membrane Protein Ywk-Ii |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinNucleus |
| Alternative Antibody Names | Anti-Amyloid Beta Precursor Like Protein 2 antibodyAnti-Apph antibodyAnti-Amyloid Beta antibodyAnti-A4 Precursor-Like Protein 2 antibodyAnti-Amyloid Protein Homolog antibodyAnti-Amyloid-Like Protein 2 antibodyAnti-Aplp-2 antibodyAnti-Cdei Box-Binding Protein antibodyAnti-Cdebp antibodyAnti-Sperm Membrane Protein Ywk-Ii antibodyAnti-APLP2 antibodyAnti-APPL2 antibody |
Information sourced from Uniprot.org