Anti-APAF1 antibody (501-550 aa) (STJ96743)

SKU:
STJ96743
€58.80 - €313.20
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Short Description :Rabbit polyclonal anti-Apoptotic protease-activating factor 1 (501-550 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IHC/IF/ELISA
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-1:2000
IHC-P 1:100-1:300
ELISA 1:20000
IF 1:50-200
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:APAF1
Gene ID:317
Uniprot ID:APAF_HUMAN
Immunogen:The antiserum was produced against synthesized peptide derived from the Internal region of human APAF1 at the amino acid range 501-550
Immunogen Region:501-550 aa
Specificity:Apaf-1 Polyclonal Antibody detects endogenous levels of Apaf-1 protein.
Function Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
Protein Name Apoptotic Protease-Activating Factor 1
Apaf-1
Database Links Reactome: R-HSA-111458
Reactome: R-HSA-111459
Reactome: R-HSA-111463
Reactome: R-HSA-111464
Reactome: R-HSA-6798695
Reactome: R-HSA-6803207
Reactome: R-HSA-8953750
Reactome: R-HSA-9627069
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Apoptotic Protease-Activating Factor 1 antibody
Anti-Apaf-1 antibody
Anti-APAF1 antibody
Anti-KIAA0413 antibody

Information sourced from Uniprot.org