Anti-AP3S2 antibody (STJA0008682)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human AP3S2
General Information
| Short Description | Rabbit polyclonal anti-AP-3 complex subunit sigma-2 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AP3S2 |
| Gene ID | 10239 |
| Uniprot ID | AP3S2_HUMAN |
| Immunogen | Synthesized peptide derived from human AP3S2 |
| Specificity | This antibody detects endogenous levels of AP3S2 at Human, Mouse |
Additional Info
| Function | Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. |
| Protein Name | Ap-3 Complex Subunit Sigma-2Ap-3 Complex Subunit Sigma-3bAdaptor-Related Protein Complex 3 Subunit Sigma-2Sigma-3b-AdaptinSigma3b-AdaptinSigma-Adaptin 3b |
| Database Links | |
| Cellular Localisation | Golgi ApparatusCytoplasmic Vesicle MembranePeripheral Membrane ProteinCytoplasmic SideComponent Of The Coat Surrounding The Cytoplasmic Face Of Coated Vesicles Located At The Golgi Complex |
| Alternative Antibody Names | Anti-Ap-3 Complex Subunit Sigma-2 antibodyAnti-Ap-3 Complex Subunit Sigma-3b antibodyAnti-Adaptor-Related Protein Complex 3 Subunit Sigma-2 antibodyAnti-Sigma-3b-Adaptin antibodyAnti-Sigma3b-Adaptin antibodyAnti-Sigma-Adaptin 3b antibodyAnti-AP3S2 antibody |
Information sourced from Uniprot.org