Anti-AP3D1 antibody (520-700) (STJ115025)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal AP3D1 (520-700) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AP3D1 |
| Gene ID | 8943 |
| Uniprot ID | AP3D1_HUMAN |
| Immunogen Region | 520-700 |
| Immunogen Sequence | AVYVQNVVKLYASILQQKEQ AGEAEGAQAVTQLMVDRLPQ FVQSADLEVQERASCILQLV KHIQKLQAKDVPVAEEVSAL FAGELNPVAPKAQKKVPVPE GLDLDAWINEPLSDSESEDE RPRAVFHEEEQRRPKHRPSE ADEEELARRREARKQEQANN PFYIKSSPSPQKRYQDTPGV E |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 520-700 of human AP3D1 (NP_003929.4). |
Additional Info
| Tissue Specificity | Present in all adult tissues examined with the highest levels in skeletal muscle, heart, pancreas and testis. |
| Function | Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Involved in process of CD8+ T-cell and NK cell degranulation. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. |
| Protein Name | Ap-3 Complex Subunit Delta-1Ap-3 Complex Subunit DeltaAdaptor-Related Protein Complex 3 Subunit Delta-1Delta-Adaptin |
| Database Links | |
| Cellular Localisation | CytoplasmGolgi Apparatus MembranePeripheral Membrane ProteinCytoplasmic Side |
| Alternative Antibody Names | Anti-Ap-3 Complex Subunit Delta-1 antibodyAnti-Ap-3 Complex Subunit Delta antibodyAnti-Adaptor-Related Protein Complex 3 Subunit Delta-1 antibodyAnti-Delta-Adaptin antibodyAnti-AP3D1 antibodyAnti-PRO0039 antibody |
Information sourced from Uniprot.org