Anti-AP3B2 antibody (STJA0008179)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human AP3B2
General Information
| Short Description | Rabbit polyclonal anti-AP-3 complex subunit beta-2 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AP3B2 |
| Gene ID | 8120 |
| Uniprot ID | AP3B2_HUMAN |
| Immunogen | Synthesized peptide derived from human AP3B2 |
| Specificity | This antibody detects endogenous levels of AP3B2 at Human, Mouse |
Additional Info
| Function | Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. |
| Protein Name | Ap-3 Complex Subunit Beta-2Adaptor Protein Complex Ap-3 Subunit Beta-2Adaptor-Related Protein Complex 3 Subunit Beta-2Beta-3b-AdaptinClathrin Assembly Protein Complex 3 Beta-2 Large ChainNeuron-Specific Vesicle Coat Protein Beta-Nap |
| Database Links | |
| Cellular Localisation | Cytoplasmic VesicleClathrin-Coated Vesicle MembranePeripheral Membrane ProteinCytoplasmic SideGolgi ApparatusComponent Of The Coat Surrounding The Cytoplasmic Face Of Coated Vesicles Located At The Golgi Complex |
| Alternative Antibody Names | Anti-Ap-3 Complex Subunit Beta-2 antibodyAnti-Adaptor Protein Complex Ap-3 Subunit Beta-2 antibodyAnti-Adaptor-Related Protein Complex 3 Subunit Beta-2 antibodyAnti-Beta-3b-Adaptin antibodyAnti-Clathrin Assembly Protein Complex 3 Beta-2 Large Chain antibodyAnti-Neuron-Specific Vesicle Coat Protein Beta-Nap antibodyAnti-AP3B2 antibody |
Information sourced from Uniprot.org