| Host: |
Rabbit |
| Applications: |
IHC/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Ap-1 Complex Subunit Sigma-3 is suitable for use in Immunohistochemistry and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Purification: |
Antigen affinity purification |
| Concentration: |
0.96 mg/mL |
| Dilution Range: |
IHC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for long term, and avoid freeze-thaw cycles. |
| Tissue Specificity | Widely expressed. |
| Function | Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Involved in TLR3 trafficking. |
| Protein Name | Ap-1 Complex Subunit Sigma-3Adaptor Protein Complex Ap-1 Subunit Sigma-1cAdaptor-Related Protein Complex 1 Subunit Sigma-1cClathrin Assembly Protein Complex 1 Sigma-1c Small ChainGolgi Adaptor Ha1/Ap1 Adaptin Sigma-1c SubunitSigma 1c Subunit Of Ap-1 ClathrinSigma-Adaptin 1cSigma1c-Adaptin |
| Database Links | Reactome: R-HSA-164940Reactome: R-HSA-2132295Reactome: R-HSA-432720Reactome: R-HSA-432722 |
| Cellular Localisation | Golgi ApparatusCytoplasmic Vesicle MembranePeripheral Membrane ProteinCytoplasmic SideMembraneClathrin-Coated PitComponent Of The Coat Surrounding The Cytoplasmic Face Of Coated Vesicles Located At The Golgi Complex |
| Alternative Antibody Names | Anti-Ap-1 Complex Subunit Sigma-3 antibodyAnti-Adaptor Protein Complex Ap-1 Subunit Sigma-1c antibodyAnti-Adaptor-Related Protein Complex 1 Subunit Sigma-1c antibodyAnti-Clathrin Assembly Protein Complex 1 Sigma-1c Small Chain antibodyAnti-Golgi Adaptor Ha1/Ap1 Adaptin Sigma-1c Subunit antibodyAnti-Sigma 1c Subunit Of Ap-1 Clathrin antibodyAnti-Sigma-Adaptin 1c antibodyAnti-Sigma1c-Adaptin antibodyAnti-AP1S3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
