Anti-AP1S3 antibody (STJA0004693)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenFusion protein of human AP1S3
General Information
| Short Description | Rabbit polyclonal anti-Ap-1 Complex Subunit Sigma-3 for use in IHC and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1.26 mg/mL |
| Purification | Antigen affinity purification |
| Dilution Range | IHC 1:100-1:300 |
| Formulation | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | AP1S3 |
| Gene ID | 130340 |
| Uniprot ID | AP1S3_HUMAN |
| Immunogen | Fusion protein of human AP1S3 |
Additional Info
| Tissue Specificity | Widely expressed. |
| Function | Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Involved in TLR3 trafficking. |
| Protein Name | Ap-1 Complex Subunit Sigma-3Adaptor Protein Complex Ap-1 Subunit Sigma-1cAdaptor-Related Protein Complex 1 Subunit Sigma-1cClathrin Assembly Protein Complex 1 Sigma-1c Small ChainGolgi Adaptor Ha1/Ap1 Adaptin Sigma-1c SubunitSigma 1c Subunit Of Ap-1 ClathrinSigma-Adaptin 1cSigma1c-Adaptin |
| Database Links | Reactome: R-HSA-164940Reactome: R-HSA-2132295Reactome: R-HSA-432720Reactome: R-HSA-432722 |
| Cellular Localisation | Golgi ApparatusCytoplasmic Vesicle MembranePeripheral Membrane ProteinCytoplasmic SideMembraneClathrin-Coated PitComponent Of The Coat Surrounding The Cytoplasmic Face Of Coated Vesicles Located At The Golgi Complex |
| Alternative Antibody Names | Anti-Ap-1 Complex Subunit Sigma-3 antibodyAnti-Adaptor Protein Complex Ap-1 Subunit Sigma-1c antibodyAnti-Adaptor-Related Protein Complex 1 Subunit Sigma-1c antibodyAnti-Clathrin Assembly Protein Complex 1 Sigma-1c Small Chain antibodyAnti-Golgi Adaptor Ha1/Ap1 Adaptin Sigma-1c Subunit antibodyAnti-Sigma 1c Subunit Of Ap-1 Clathrin antibodyAnti-Sigma-Adaptin 1c antibodyAnti-Sigma1c-Adaptin antibodyAnti-AP1S3 antibody |
Information sourced from Uniprot.org