| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-AP1M1 (1-160) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
AP1M1 |
| Gene ID: |
8907 |
| Uniprot ID: |
AP1M1_HUMAN |
| Immunogen Region: |
1-160 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human AP1M1 (NP_115882.1). |
| Immunogen Sequence: |
MSASAVYVLDLKGKVLICRN YRGDVDMSEVEHFMPILMEK EEEGMLSPILAHGGVRFMWI KHNNLYLVATSKKNACVSLV FSFLYKVVQVFSEYFKELEE ESIRDNFVIIYELLDELMDF GYPQTTDSKILQEYITQEGH KLETGAPRPPATVTNAVSWR |
| Post Translational Modifications | Phosphorylation of membrane-bound AP1M1/AP1M2 increases its affinity for sorting signals. |
| Function | Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. |
| Protein Name | Ap-1 Complex Subunit Mu-1Ap-Mu Chain Family Member Mu1aAdaptor Protein Complex Ap-1 Subunit Mu-1Adaptor-Related Protein Complex 1 Subunit Mu-1Clathrin Assembly Protein Complex 1 Mu-1 Medium Chain 1Clathrin Coat Assembly Protein Ap47Clathrin Coat-Associated Protein Ap47Golgi Adaptor Ha1/Ap1 Adaptin Mu-1 SubunitMu-Adaptin 1Mu1a-Adaptin |
| Database Links | Reactome: R-HSA-164940Reactome: R-HSA-2132295Reactome: R-HSA-432720Reactome: R-HSA-432722Reactome: R-HSA-6798695 |
| Cellular Localisation | Golgi ApparatusCytoplasmic VesicleClathrin-Coated Vesicle MembranePeripheral Membrane ProteinCytoplasmic SideComponent Of The Coat Surrounding The Cytoplasmic Face Of Coated Vesicles Located At The Golgi Complex |
| Alternative Antibody Names | Anti-Ap-1 Complex Subunit Mu-1 antibodyAnti-Ap-Mu Chain Family Member Mu1a antibodyAnti-Adaptor Protein Complex Ap-1 Subunit Mu-1 antibodyAnti-Adaptor-Related Protein Complex 1 Subunit Mu-1 antibodyAnti-Clathrin Assembly Protein Complex 1 Mu-1 Medium Chain 1 antibodyAnti-Clathrin Coat Assembly Protein Ap47 antibodyAnti-Clathrin Coat-Associated Protein Ap47 antibodyAnti-Golgi Adaptor Ha1/Ap1 Adaptin Mu-1 Subunit antibodyAnti-Mu-Adaptin 1 antibodyAnti-Mu1a-Adaptin antibodyAnti-AP1M1 antibodyAnti-CLTNM antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
