Anti-AP1G1 antibody (723-822) [S0MR] (STJ11103000)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal AP1G1 (723-822) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S0MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:2000IHC-P:1:100-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AP1G1 |
| Gene ID | 164 |
| Uniprot ID | AP1G1_HUMAN |
| Immunogen Region | 723-822 |
| Immunogen Sequence | RSNTNPSVTVITIQASNSTE LDMTDFVFQAAVPKTFQLQL LSPSSSIVPAFNTGTITQVI KVLNPQKQQLRMRIKLTYNH KGSAMQDLAEVNNFPPQSWQ |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 723-822 of human AP1G1 (O43747). |
Additional Info
| Tissue Specificity | Widely expressed. |
| Function | Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. In association with AFTPH/aftiphilin in the aftiphilin/p200/gamma-synergin complex, involved in the trafficking of transferrin from early to recycling endosomes, and the membrane trafficking of furin and the lysosomal enzyme cathepsin D between the trans-Golgi network (TGN) and endosomes. |
| Protein Name | Ap-1 Complex Subunit Gamma-1Adaptor Protein Complex Ap-1 Subunit Gamma-1Adaptor-Related Protein Complex 1 Subunit Gamma-1Clathrin Assembly Protein Complex 1 Gamma-1 Large ChainGamma1-AdaptinGolgi Adaptor Ha1/Ap1 Adaptin Subunit Gamma-1 |
| Database Links | Reactome: R-HSA-164940Reactome: R-HSA-2132295Reactome: R-HSA-432720Reactome: R-HSA-432722 |
| Cellular Localisation | Golgi ApparatusCytoplasmic VesicleClathrin-Coated Vesicle MembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmPerinuclear RegionClathrin-Coated VesicleMembraneClathrin-Coated PitComponent Of The Coat Surrounding The Cytoplasmic Face Of Coated Vesicles Located At The Golgi ComplexCo-Localizes With Aftph/Aftiphilin In The Cytoplasm |
| Alternative Antibody Names | Anti-Ap-1 Complex Subunit Gamma-1 antibodyAnti-Adaptor Protein Complex Ap-1 Subunit Gamma-1 antibodyAnti-Adaptor-Related Protein Complex 1 Subunit Gamma-1 antibodyAnti-Clathrin Assembly Protein Complex 1 Gamma-1 Large Chain antibodyAnti-Gamma1-Adaptin antibodyAnti-Golgi Adaptor Ha1/Ap1 Adaptin Subunit Gamma-1 antibodyAnti-AP1G1 antibodyAnti-ADTG antibodyAnti-CLAPG1 antibody |
Information sourced from Uniprot.org