Anti-AP1B1 antibody (700-800) (STJ118734)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal AP1B1 (700-800) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AP1B1 |
| Gene ID | 162 |
| Uniprot ID | AP1B1_HUMAN |
| Immunogen Region | 700-800 |
| Immunogen Sequence | SDLFDLTSGVGTLSGSYVAP KAVWLPAMKAKGLEISGTFT RQVGSISMDLQLTNKALQVM TDFAIQFNRNSFGLAPAAPL QVHAPLSPNQTVEISLPLST V |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 700-800 of human AP1B1 (NP_001118.3). |
Additional Info
| Tissue Specificity | Widely expressed. |
| Function | Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. |
| Protein Name | Ap-1 Complex Subunit Beta-1Adaptor Protein Complex Ap-1 Subunit Beta-1Adaptor-Related Protein Complex 1 Subunit Beta-1Beta-1-AdaptinBeta-Adaptin 1Clathrin Assembly Protein Complex 1 Beta Large ChainGolgi Adaptor Ha1/Ap1 Adaptin Beta Subunit |
| Database Links | Reactome: R-HSA-164940Reactome: R-HSA-2132295Reactome: R-HSA-432720Reactome: R-HSA-432722 |
| Cellular Localisation | Golgi ApparatusCytoplasmic VesicleClathrin-Coated Vesicle MembranePeripheral Membrane ProteinCytoplasmic SideComponent Of The Coat Surrounding The Cytoplasmic Face Of Coated Vesicles Located At The Golgi Complex |
| Alternative Antibody Names | Anti-Ap-1 Complex Subunit Beta-1 antibodyAnti-Adaptor Protein Complex Ap-1 Subunit Beta-1 antibodyAnti-Adaptor-Related Protein Complex 1 Subunit Beta-1 antibodyAnti-Beta-1-Adaptin antibodyAnti-Beta-Adaptin 1 antibodyAnti-Clathrin Assembly Protein Complex 1 Beta Large Chain antibodyAnti-Golgi Adaptor Ha1/Ap1 Adaptin Beta Subunit antibodyAnti-AP1B1 antibodyAnti-ADTB1 antibodyAnti-BAM22 antibodyAnti-CLAPB2 antibody |
Information sourced from Uniprot.org