Anti-AP-A antibody [R08-6M5] (STJA0037038)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human Aminopeptidase A/CD249
General Information
| Short Description | Rabbit monoclonal anti-AP-A for use in WB and IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R08-6M5 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | ENPEP |
| Gene ID | 2028 |
| Uniprot ID | AMPE_HUMAN |
| Immunogen | A synthesized peptide derived from human Aminopeptidase A/CD249 |
Additional Info
| Tissue Specificity | Expressed in choriocarcinoma cancer cell lines (at protein level). Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues. |
| Function | Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II. |
| Protein Name | Glutamyl AminopeptidaseEapAminopeptidase AAp-ADifferentiation Antigen Gp160Cd Antigen Cd249 |
| Database Links | Reactome: R-HSA-2022377 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Glutamyl Aminopeptidase antibodyAnti-Eap antibodyAnti-Aminopeptidase A antibodyAnti-Ap-A antibodyAnti-Differentiation Antigen Gp160 antibodyAnti-Cd Antigen Cd249 antibodyAnti-ENPEP antibody |
Information sourced from Uniprot.org