Anti-AP-1 complex subunit beta-1 antibody (11-29 aa) (STJA0040955)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeMixed
ImmunogenA synthetic peptide (C-KKGEIFELKAELNSDKKEK) corresponding to the amino acids 11-29 of human AP-1 complex subunit beta-1 conjugated to diphtheria toxin has been used as the immunogen. The peptide is homologous with the corresponding sequence derived f
General Information
| Short Description | Rabbit polyclonal anti-AP-1 complex subunit beta-1 (11-29 aa) for use in ICC, IHC-F, IHC-P and WB in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ICC/IHC-F/IHC-P/WB |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | Mixed |
| Conjugation | Unconjugated |
| Purification | Whole serum |
| Dilution Range | WB 1:100-1:10000IHC 1:1000-1:5000 |
| Storage Instruction | Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at-20°C for a higher stability, and at 2-8°C with an appropriate antibacterial |
Target Information
| Gene Symbol | AP1B1 |
| Gene ID | 162 |
| Uniprot ID | AP1B1_HUMAN |
| Immunogen | A synthetic peptide (C-KKGEIFELKAELNSDKKEK) corresponding to the amino acids 11-29 of human AP-1 complex subunit beta-1 conjugated to diphtheria toxin has been used as the immunogen. The peptide is homologous with the corresponding sequence derived f |
| Immunogen Region | 11-29 aa |
| Immunogen Sequence | Human |
| Specificity | This antibody has been shown to be specific for AP-1 complex subunit beta-1. Rat and human, other species have not yet tested. |
Additional Info
| Tissue Specificity | Widely expressed. |
| Function | Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. |
| Protein Name | Ap-1 Complex Subunit Beta-1Adaptor Protein Complex Ap-1 Subunit Beta-1Adaptor-Related Protein Complex 1 Subunit Beta-1Beta-1-AdaptinBeta-Adaptin 1Clathrin Assembly Protein Complex 1 Beta Large ChainGolgi Adaptor Ha1/Ap1 Adaptin Beta Subunit |
| Database Links | Reactome: R-HSA-164940Reactome: R-HSA-2132295Reactome: R-HSA-432720Reactome: R-HSA-432722 |
| Cellular Localisation | Golgi ApparatusCytoplasmic VesicleClathrin-Coated Vesicle MembranePeripheral Membrane ProteinCytoplasmic SideComponent Of The Coat Surrounding The Cytoplasmic Face Of Coated Vesicles Located At The Golgi Complex |
| Alternative Antibody Names | Anti-Ap-1 Complex Subunit Beta-1 antibodyAnti-Adaptor Protein Complex Ap-1 Subunit Beta-1 antibodyAnti-Adaptor-Related Protein Complex 1 Subunit Beta-1 antibodyAnti-Beta-1-Adaptin antibodyAnti-Beta-Adaptin 1 antibodyAnti-Clathrin Assembly Protein Complex 1 Beta Large Chain antibodyAnti-Golgi Adaptor Ha1/Ap1 Adaptin Beta Subunit antibodyAnti-AP1B1 antibodyAnti-ADTB1 antibodyAnti-BAM22 antibodyAnti-CLAPB2 antibody |
Information sourced from Uniprot.org