| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Anoctamin-2 (362-412 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ANO2 |
| Gene ID: |
57101 |
| Uniprot ID: |
ANO2_HUMAN |
| Immunogen Region: |
362-412 aa |
| Specificity: |
This antibody detects endogenous levels of ANO2 at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human ANO2 at the amino acid range 362-412 |
| Function | Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor-sensing receptors (OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be the underlying chloride channel involved in this process. May mediate light perception amplification in retina. |
| Protein Name | Anoctamin-2Transmembrane Protein 16b |
| Database Links | Reactome: R-HSA-2672351Reactome: R-HSA-381753Reactome: R-HSA-9733458 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Anoctamin-2 antibodyAnti-Transmembrane Protein 16b antibodyAnti-ANO2 antibodyAnti-C12orf3 antibodyAnti-TMEM16B antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
