Anti-Annexin A5 antibody [M017] (STJA0041044)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenClone M017 was generated from a proprietary antigen related to human Annexin A5 in the MDA-MB-231 breast cancer cell line.
General Information
| Short Description | Mouse monoclonal anti-Annexin A5 for use in ELISA, WB and IP in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB/IP |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | M017 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Purification | Protein G Purified |
| Dilution Range | WB 1:1000IP 1:100 |
| Formulation | PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol |
| Storage Instruction | Storage at-20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at-20°C. |
Target Information
| Gene Symbol | ANXA5 |
| Gene ID | 308 |
| Uniprot ID | ANXA5_HUMAN |
| Immunogen | Clone M017 was generated from a proprietary antigen related to human Annexin A5 in the MDA-MB-231 breast cancer cell line. |
| Immunogen Sequence | Human |
| Specificity | Clone M017 detects a 35 kDa* protein corresponding to the molecular mass of Annexin A5 on SDS-PAGE immunoblots of human A431, MDA-MB-231, MeWo, and PC3 cells, as well as human skin, breast, lung, and brain. The antibody works for ELISA, western blot, |
Additional Info
| Post Translational Modifications | S-nitrosylation is induced by interferon-gamma and oxidatively-modified low-densitity lipoprotein (LDL(ox)) possibly implicating the iNOS-S100A8/9 transnitrosylase complex. |
| Function | This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. |
| Protein Name | Annexin A5Anchorin CiiAnnexin VAnnexin-5Calphobindin ICpb-IEndonexin IiLipocortin VPlacental Anticoagulant Protein 4Pp4Placental Anticoagulant Protein IPap-IThromboplastin InhibitorVascular Anticoagulant-AlphaVac-Alpha |
| Database Links | Reactome: R-HSA-114608 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Annexin A5 antibodyAnti-Anchorin Cii antibodyAnti-Annexin V antibodyAnti-Annexin-5 antibodyAnti-Calphobindin I antibodyAnti-Cpb-I antibodyAnti-Endonexin Ii antibodyAnti-Lipocortin V antibodyAnti-Placental Anticoagulant Protein 4 antibodyAnti-Pp4 antibodyAnti-Placental Anticoagulant Protein I antibodyAnti-Pap-I antibodyAnti-Thromboplastin Inhibitor antibodyAnti-Vascular Anticoagulant-Alpha antibodyAnti-Vac-Alpha antibodyAnti-ANXA5 antibodyAnti-ANX5 antibodyAnti-ENX2 antibodyAnti-PP4 antibody |
Information sourced from Uniprot.org