| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Ankyrin repeat and sterile alpha motif domain-containing protein 1B is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ANKS1B |
| Gene ID: |
56899 |
| Uniprot ID: |
ANS1B_HUMAN |
| Specificity: |
This antibody detects endogenous levels of ANKS1B at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human ANKS1B |
| Post Translational Modifications | Isoform 3 nuclear translocation requires an NMDAR-dependent proteolytic cleavage. |
| Function | Isoform 2 may participate in the regulation of nucleoplasmic coilin protein interactions in neuronal and transformed cells. Isoform 3 can regulate global protein synthesis by altering nucleolar numbers. Isoform 4 may play a role as a modulator of APP processing. Overexpression can down-regulate APP processing. |
| Protein Name | Ankyrin Repeat And Sterile Alpha Motif Domain-Containing Protein 1bAmyloid-Beta Protein Intracellular Domain-Associated Protein 1Aida-1E2a-Pbx1-Associated ProteinEb-1 |
| Cellular Localisation | CytoplasmIsoform 2: NucleusIsoform 3: Postsynaptic DensityCell ProjectionDendritic SpineNucleusCajal BodyThe Synaptic Localization Requires Dlg4 InteractionTranslocation To The Nucleus In Response To Stimulation Of Nmda Receptors (Nmdars) In A Calcium-Independent MannerIsoform 4: NucleusThe Interaction With App Causes Its Partial Exclusion From The NucleusWhen App Is OverexpressedIsoform 6: Nucleus |
| Alternative Antibody Names | Anti-Ankyrin Repeat And Sterile Alpha Motif Domain-Containing Protein 1b antibodyAnti-Amyloid-Beta Protein Intracellular Domain-Associated Protein 1 antibodyAnti-Aida-1 antibodyAnti-E2a-Pbx1-Associated Protein antibodyAnti-Eb-1 antibodyAnti-ANKS1B antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
