| Short Description : | Rabbit polyclonal anti-Ankyrin repeat domain-containing protein 13A for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ANKRD13A |
| Gene ID: | 88455 |
| Uniprot ID: | AN13A_HUMAN |
| Immunogen: | Synthesized peptide derived from human ANKRD13A |
| Specificity: | This antibody detects endogenous levels of ANKRD13A at Human, Mouse |
| Function | Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane. |
| Protein Name | Ankyrin Repeat Domain-Containing Protein 13aProtein Ke03 |
| Database Links | |
| Cellular Localisation | Cell MembraneLate EndosomeInteraction With Egfr May Enhance Association With The Cell Membrane |
| Alternative Antibody Names | Anti-Ankyrin Repeat Domain-Containing Protein 13a antibodyAnti-Protein Ke03 antibodyAnti-ANKRD13A antibodyAnti-ANKRD13 antibody |
Information sourced from Uniprot.org
