• Immunofluorescence analysis of Neuro-2a cells using ANK3 Rabbit polyclonal antibody (STJ11103956) at dilution of 1:200 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of SH-SY5Y cells using ANK3 Rabbit polyclonal antibody (STJ11103956) at dilution of 1:100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.

Anti-ANK3 antibody (833-977) (STJ11103956)

SKU:
STJ11103956

£116.50 - £543.50
Current Stock:
Host: Rabbit
Applications: IF
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Ankyrin-3 (833-977) is suitable for use in Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ANK3
Gene ID: 288
Uniprot ID: ANK3_HUMAN
Immunogen Region: 833-977
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 833-977 of human ANK3 (NP_066267.2).
Immunogen Sequence: KMNVPETMNEVLDMSDDEVR KANAPEMLSDGEYISDVEEG EDAMTGDTDKYLGPQDLKEL GDDSLPAEGYMGFSLGARSA SLRSFSSDRSYTLNRSSYAR DSMMIEELLVPSKEQHLTFT REFDSDSLRHYSWAADTLDN VNLVS
Tissue Specificity Expressed in brain, neurons, muscles and other tissues.
Function In skeletal muscle, required for costamere localization of DMD and betaDAG1. Membrane-cytoskeleton linker. May participate in the maintenance/targeting of ion channels and cell adhesion molecules at the nodes of Ranvier and axonal initial segments. Regulates KCNA1 channel activity in function of dietary Mg(2+) levels, and thereby contributes to the regulation of renal Mg(2+) reabsorption. Isoform 5: May be part of a Golgi-specific membrane cytoskeleton in association with beta-spectrin.
Protein Name Ankyrin-3
Ank-3
Ankyrin-G
Database Links Reactome: R-HSA-445095
Reactome: R-HSA-6807878
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Projection
Axon
Cell Membrane
Sarcolemma
Postsynaptic Cell Membrane
Lysosome
T-Tubule
In Skeletal Muscle
Localized At Costameres And Neuromuscular Junctions
In Macrophages
Associated With Lysosomes
Isoform 5: Cytoplasm
Golgi Apparatus
Alternative Antibody Names Anti-Ankyrin-3 antibody
Anti-Ank-3 antibody
Anti-Ankyrin-G antibody
Anti-ANK3 antibody

Information sourced from Uniprot.org

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