Anti-AMIGO2 antibody (270-350 aa) (STJ192476)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 270-350
General Information
| Short Description | Rabbit polyclonal anti-Amphoterin-induced protein 2 (270-350 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AMIGO2 |
| Gene ID | 347902 |
| Uniprot ID | AMGO2_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 270-350 |
| Immunogen Region | 270-350 aa |
| Specificity | AMGO2 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas. |
| Protein Name | Amphoterin-Induced Protein 2Amigo-2Alivin-1Differentially Expressed In Gastric AdenocarcinomasDega |
| Database Links | Reactome: R-HSA-9013149Reactome: R-HSA-9013423 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinNucleusAssociated With Nucleus As Well As Plasma MembraneRestricted To Somata Of Cerebellar As Well As Hippocampal Neurons |
| Alternative Antibody Names | Anti-Amphoterin-Induced Protein 2 antibodyAnti-Amigo-2 antibodyAnti-Alivin-1 antibodyAnti-Differentially Expressed In Gastric Adenocarcinomas antibodyAnti-Dega antibodyAnti-AMIGO2 antibodyAnti-ALI1 antibody |
Information sourced from Uniprot.org