Anti-AMHR2 antibody (18-144) [S5022RM] (STJ11105022)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Muellerian Hormone Type-2 Receptor (18-144) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S5022RM |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:5000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AMHR2 |
| Gene ID | 269 |
| Uniprot ID | AMHR2_HUMAN |
| Immunogen Region | 18-144 |
| Immunogen Sequence | PPNRRTCVFFEAPGVRGSTK TLGELLDTGTELPRAIRCLY SRCCFGIWNLTQDRAQVEMQ GCRDSDEPGCESLHCDPSPR AHPSPGSTLFTCSCGTDFCN ANYSHLPPPGSPGTPGSQGP QAAPGES |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 18-144 of human AMHR2 (NP_065434.1). |
Additional Info
| Function | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. |
| Protein Name | Anti-Muellerian Hormone Type-2 ReceptorAnti-Muellerian Hormone Type Ii ReceptorAmh Type Ii ReceptorMis Type Ii ReceptorMisriiMrii |
| Database Links | Reactome: R-HSA-201451 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Anti-Muellerian Hormone Type-2 Receptor antibodyAnti-Anti-Muellerian Hormone Type Ii Receptor antibodyAnti-Amh Type Ii Receptor antibodyAnti-Mis Type Ii Receptor antibodyAnti-Misrii antibodyAnti-Mrii antibodyAnti-AMHR2 antibodyAnti-AMHR antibodyAnti-MISR2 antibody |
Information sourced from Uniprot.org