Anti-AMACR+P63+HMW CK antibody [13H4+4A4+34 Beta E12] (STJ180008)

Name: Anti-AMACR+P63+HMW CK antibody [13H4+4A4+34 Beta E12] (STJ180008)
SKU: STJ180008
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⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityMonoclonal

HostRabbit, Mouse

ConjugationUnconjugated

IsotypeIgG/IgG1ak/IgG2a

ImmunogenHuman AMACR (P504S) , p63, and CKHMW (34 Beta E12) polypeptides

STJ180008

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Short Description	Rabbit, Mouse monoclonal AMACR+P63+HMW CK antibody for use in IHC-P in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications	IHC-P
Host	Rabbit, Mouse
Reactivity	Human
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Monoclonal
Clone ID	13H4+4A4+34 Beta E12
Isotype	IgG/IgG1ak/IgG2a
Conjugation	Unconjugated
Purification	Affinity purified
Dilution Range	1:50
Formulation	Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin
Storage Instruction	Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C.

Gene Symbol	AMACR
Gene ID	23600
Uniprot ID	AMACR_HUMAN
Immunogen	Human AMACR (P504S) , p63, and CKHMW (34 Beta E12) polypeptides
Specificity	Positive control: Prostate intraepithelial neoplasia (PIN)

Function	Catalyzes the interconversion of (R)- and (S)-stereoisomers of alpha-methyl-branched-chain fatty acyl-CoA esters. Acts only on coenzyme A thioesters, not on free fatty acids, and accepts as substrates a wide range of alpha-methylacyl-CoAs, including pristanoyl-CoA, trihydroxycoprostanoyl-CoA (an intermediate in bile acid synthesis), and arylpropionic acids like the anti-inflammatory drug ibuprofen (2-(4-isobutylphenyl)propionic acid) but neither 3-methyl-branched nor linear-chain acyl-CoAs.
Protein Name	Alpha-Methylacyl-Coa Racemase 2-Methylacyl-Coa Racemase
Database Links	Reactome: R-HSA-193368 Reactome: R-HSA-193775 Reactome: R-HSA-389887 Reactome: R-HSA-9033241
Cellular Localisation	Peroxisome Mitochondrion
Alternative Antibody Names	Anti-Alpha-Methylacyl-Coa Racemase antibody Anti-2-Methylacyl-Coa Racemase antibody Anti-AMACR antibody

Information sourced from Uniprot.org