Anti-ALX1 antibody (STJA0008042)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human ALX1
General Information
| Short Description | Rabbit polyclonal anti-ALX homeobox protein 1 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ALX1 |
| Gene ID | 8092 |
| Uniprot ID | ALX1_HUMAN |
| Immunogen | Synthesized peptide derived from human ALX1 |
| Specificity | This antibody detects endogenous levels of ALX1 at Human, Mouse, Rat |
Additional Info
| Post Translational Modifications | Acetylated at Lys-131 by EP300.increases interaction with EP300 and stimulates ALX1 transcriptional activity. |
| Function | Sequence-specific DNA-binding transcription factor that binds palindromic sequences within promoters and may activate or repress the transcription of a subset of genes. Most probably regulates the expression of genes involved in the development of mesenchyme-derived craniofacial structures. Early on in development, it plays a role in forebrain mesenchyme survival. May also induce epithelial to mesenchymal transition (EMT) through the expression of SNAI1. |
| Protein Name | Alx Homeobox Protein 1Cartilage Homeoprotein 1Cart-1 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Alx Homeobox Protein 1 antibodyAnti-Cartilage Homeoprotein 1 antibodyAnti-Cart-1 antibodyAnti-ALX1 antibodyAnti-CART1 antibody |
Information sourced from Uniprot.org