Anti-Alpha2-antiplasmin antibody (Internal) (STJ71657)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-Alpha2-antiplasmin (Internal) is suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunofluorescence and Flow Cytometry research applications. |
| Applications | Pep-ELISA/WB/IHC/IF/FC |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 70kDa band observed in lysates of cell line HepG2 (calculated MW of 54.6kDa according to NP_000925.2). The observed molecular weight is observed by other sources. Recommended co |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | SERPINF2 |
| Gene ID | 5345 |
| Uniprot ID | A2AP_HUMAN |
| Accession Number | NP_000925.2; NP_001159393.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | KDFLQSLKGFPRGDK |
| Specificity | This antibody is expected to recognise both reported isoforms (NP_000925.2; NP_001159393.1). Reported variants represent identical protein (NP_000925.2; NP_001159392.1). |
Additional Info
| Post Translational Modifications | Proteolytically cleaved at Pro-39 by both the prolyl endopeptidase FAP form and antiplasmin-cleaving enzyme FAP soluble form to generate mature alpha-2-antiplasmin. |
| Function | Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin. |
| Protein Name | Alpha-2-AntiplasminAlpha-2-ApAlpha-2-Plasmin InhibitorAlpha-2-PiSerpin F2 |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-75205 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Alpha-2-Antiplasmin antibodyAnti-Alpha-2-Ap antibodyAnti-Alpha-2-Plasmin Inhibitor antibodyAnti-Alpha-2-Pi antibodyAnti-Serpin F2 antibodyAnti-SERPINF2 antibodyAnti-AAP antibodyAnti-PLI antibody |
Information sourced from Uniprot.org