Anti-alpha Sarcoglycan antibody [R04-6A5] (STJA0034007)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human alpha Sarcoglycan
General Information
| Short Description | Rabbit monoclonal anti-alpha Sarcoglycan for use in WB, IHC-P and IP in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IP |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R04-6A5 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IP 1:20 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | SGCA |
| Gene ID | 6442 |
| Uniprot ID | SGCA_HUMAN |
| Immunogen | A synthetic peptide of human alpha Sarcoglycan |
Additional Info
| Tissue Specificity | Most strongly expressed in skeletal muscle. Also expressed in cardiac muscle and, at much lower levels, in lung. In the fetus, most abundant in cardiac muscle and, at lower levels, in lung. Also detected in liver and kidney. Not expressed in brain. |
| Function | Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. |
| Protein Name | Alpha-SarcoglycanAlpha-Sg50 Kda Dystrophin-Associated Glycoprotein50dagAdhalinDystroglycan-2 |
| Database Links | Reactome: R-HSA-9913351 |
| Cellular Localisation | Cell MembraneSarcolemmaSingle-Pass Type I Membrane ProteinCytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Alpha-Sarcoglycan antibodyAnti-Alpha-Sg antibodyAnti-50 Kda Dystrophin-Associated Glycoprotein antibodyAnti-50dag antibodyAnti-Adhalin antibodyAnti-Dystroglycan-2 antibodyAnti-SGCA antibodyAnti-ADL antibodyAnti-DAG2 antibody |
Information sourced from Uniprot.org