Anti-Alpha Fodrin antibody [SRM13379] (STJ11108109)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
General Information
| Short Description | Rabbit monoclonal Spectrin Alpha Chain-Non-Erythrocytic 1 antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM13379 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB, 1:500-1:1000IHC-P, 1:50-1:200ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SPTAN1 |
| Gene ID | 6709 |
| Uniprot ID | SPTN1_HUMAN |
| Immunogen | Synthetic peptide. This information is considered to be commercially sensitive. |
| Immunogen Sequence | Human |
Additional Info
| Function | Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane. |
| Protein Name | Spectrin Alpha Chain - Non-Erythrocytic 1Alpha-Ii SpectrinFodrin Alpha ChainSpectrin - Non-Erythroid Alpha Subunit |
| Database Links | Reactome: R-HSA-264870Reactome: R-HSA-373753Reactome: R-HSA-375165Reactome: R-HSA-445095Reactome: R-HSA-5673001Reactome: R-HSA-6798695Reactome: R-HSA-6807878Reactome: R-HSA-9013420Reactome: R-HSA-9013424Reactome: R-HSA-9662360Reactome: R-HSA-9662361 |
| Cellular Localisation | CytoplasmCytoskeletonCell CortexExpressed Along The Cell Membrane In Podocytes And Presumptive Tubule Cells During Glomerulogenesis And Is Expressed Along Lateral Cell Margins In Tubule Cells |
| Alternative Antibody Names | Anti-Spectrin Alpha Chain - Non-Erythrocytic 1 antibodyAnti-Alpha-Ii Spectrin antibodyAnti-Fodrin Alpha Chain antibodyAnti-Spectrin - Non-Erythroid Alpha Subunit antibodyAnti-SPTAN1 antibodyAnti-NEAS antibodyAnti-SPTA2 antibody |
Information sourced from Uniprot.org