| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:20-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ALDOA |
| Gene ID: | 226 |
| Uniprot ID: | ALDOA_HUMAN |
| Immunogen Region: | 1-348 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-348 of human ALDOA (NP_908930.1). |
| Immunogen Sequence: | MPYQYPALTPEQKKELSDIA HRIVAPGKGILAADESTGSI AKRLQSIGTENTEENRRFYR QLLLTADDRVNPCIGGVILF HETLYQKADDGRPFPQVIKS KGGVVGIKVDKGVVPLAGTN GETTTQGLDGLSERCAQYKK DGADFAKWRCVLKIGEHTPS ALAIMENANVLARYASICQQ NGIVPIVEPEILPDGDHDLK RCQYVTEKVLAAVYKALSDH HIYLEGTLLKPNMVTPGHA |
| Function | Catalyzes the reversible conversion of beta-D-fructose 1,6-bisphosphate (FBP) into two triose phosphate and plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein. |
| Protein Name | Fructose-Bisphosphate Aldolase ALung Cancer Antigen Ny-Lu-1Muscle-Type Aldolase |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-6798695Reactome: R-HSA-70171Reactome: R-HSA-70263 |
| Cellular Localisation | CytoplasmMyofibrilSarcomereI BandM LineIn Skeletal MuscleAccumulates Around The M Line And Within The I BandColocalizing With Fbp2 On Both Sides Of The Z Line In The Absence Of Ca(2+) |
| Alternative Antibody Names | Anti-Fructose-Bisphosphate Aldolase A antibodyAnti-Lung Cancer Antigen Ny-Lu-1 antibodyAnti-Muscle-Type Aldolase antibodyAnti-ALDOA antibodyAnti-ALDA antibody |
Information sourced from Uniprot.org
