Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit monoclonal antibody anti-Alpha-Aminoadipic Semialdehyde Dehydrogenase (1-100) is suitable for use in Western Blot research applications. |
Clonality: |
Monoclonal |
Clone ID: |
S4095RM |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:100-1:500 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
ALDH7A1 |
Gene ID: |
501 |
Uniprot ID: |
AL7A1_HUMAN |
Immunogen Region: |
1-100 |
Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ALDH7A1 (P49419). |
Immunogen Sequence: |
MWRLPRALCVHAAKTSKLSG PWSRPAAFMSTLLINQPQYA WLKELGLREENEGVYNGSWG GRGEVITTYCPANNEPIARV RQASVADYEETVKKAREAWK |
Tissue Specificity | Abundant in hepatoma cells and fetal cochlea, ovary, eye, heart, adrenal gland, liver and kidney. Low levels present in adult peripheral blood leukocytes and fetal brain, thymus, spleen, skeletal muscle, lung and tongue. |
Function | Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism. |
Protein Name | Alpha-Aminoadipic Semialdehyde DehydrogenaseAlpha-Aasa DehydrogenaseAldehyde Dehydrogenase Family 7 Member A1Antiquitin-1Betaine Aldehyde DehydrogenaseDelta1-Piperideine-6-Carboxylate DehydrogenaseP6c Dehydrogenase |
Database Links | Reactome: R-HSA-6798163Reactome: R-HSA-71064 |
Cellular Localisation | Isoform 2: CytoplasmCytosolNucleusIsoform 1: Mitochondrion |
Alternative Antibody Names | Anti-Alpha-Aminoadipic Semialdehyde Dehydrogenase antibodyAnti-Alpha-Aasa Dehydrogenase antibodyAnti-Aldehyde Dehydrogenase Family 7 Member A1 antibodyAnti-Antiquitin-1 antibodyAnti-Betaine Aldehyde Dehydrogenase antibodyAnti-Delta1-Piperideine-6-Carboxylate Dehydrogenase antibodyAnti-P6c Dehydrogenase antibodyAnti-ALDH7A1 antibodyAnti-ATQ1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance