Anti-ALDH4A1 antibody [SRM13450] (STJ11108180)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
General Information
| Short Description | Rabbit monoclonal Delta-1-Pyrroline-5-Carboxylate Dehydrogenase-Mitochondrial antibody for use in WB, IF, ICC, IF-P, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/IF-P/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM13450 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB, 1:5000-1:30000IF/ICC, 1:200-1:800IF-P, 1:200-1:800IHC-P, 1:200-1:2000ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS containing 50% Glycerol and 0.05% BSA, preserved with proclin300 or Sodium Azide (as specified on the Certificate of Analysis) , pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ALDH4A1 |
| Gene ID | 8659 |
| Uniprot ID | AL4A1_HUMAN |
| Immunogen | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
| Immunogen Sequence | Human |
Additional Info
| Function | Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes. |
| Protein Name | Delta-1-Pyrroline-5-Carboxylate Dehydrogenase - MitochondrialP5c DehydrogenaseAldehyde Dehydrogenase Family 4 Member A1L-Glutamate Gamma-Semialdehyde Dehydrogenase |
| Database Links | Reactome: R-HSA-389661Reactome: R-HSA-70688 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Delta-1-Pyrroline-5-Carboxylate Dehydrogenase - Mitochondrial antibodyAnti-P5c Dehydrogenase antibodyAnti-Aldehyde Dehydrogenase Family 4 Member A1 antibodyAnti-L-Glutamate Gamma-Semialdehyde Dehydrogenase antibodyAnti-ALDH4A1 antibodyAnti-ALDH4 antibodyAnti-P5CDH antibody |
Information sourced from Uniprot.org