• Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-ALDH4A1 antibody (39-89 aa) (STJ193563)

SKU:
STJ193563

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial (39-89 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ALDH4A1
Gene ID: 8659
Uniprot ID: AL4A1_HUMAN
Immunogen Region: 39-89 aa
Specificity: This antibody detects endogenous levels of AL4A1 at Human/Mouse/Rat
Immunogen: Synthesized peptide derived from the human AL4A1 at the amino acid range 39-89
Function Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes.
Protein Name Delta-1-Pyrroline-5-Carboxylate Dehydrogenase - Mitochondrial
P5c Dehydrogenase
Aldehyde Dehydrogenase Family 4 Member A1
L-Glutamate Gamma-Semialdehyde Dehydrogenase
Database Links Reactome: R-HSA-389661
Reactome: R-HSA-70688
Cellular Localisation Mitochondrion Matrix
Alternative Antibody Names Anti-Delta-1-Pyrroline-5-Carboxylate Dehydrogenase - Mitochondrial antibody
Anti-P5c Dehydrogenase antibody
Anti-Aldehyde Dehydrogenase Family 4 Member A1 antibody
Anti-L-Glutamate Gamma-Semialdehyde Dehydrogenase antibody
Anti-ALDH4A1 antibody
Anti-ALDH4 antibody
Anti-P5CDH antibody

Information sourced from Uniprot.org

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