Anti-ALDH1L1 antibody (1-250) (STJ29147)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ29147
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General Information

Short DescriptionRabbit polyclonal ALDH1L1 (1-250) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ELISA
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolALDH1L1
Gene ID10840
Uniprot IDAL1L1_HUMAN
Immunogen Region1-250
Immunogen SequenceMKIAVIGQSLFGQEVYCHLR KEGHEVVGVFTVPDKDGKAD PLGLEAEKDGVPVFKYSRWR AKGQALPDVVAKYQALGAEL NVLPFCSQFIPMEIISAPRH GSIIYHPSLLPRHRGASAIN WTLIHGDKKGGFSIFWADDG LDTGDLLLQKECEVLPDDTV STLYNRFLFPEGIKGMVQAV RLIAEGKAPRLPQPEEGATY EGIQKKETAKINWDQPAEAI HNWIRGNDKVPGAWTEACE
SpecificityRecombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ALDH1L1 (NP_036322.2).

Additional Info

Tissue Specificity Highly expressed in liver, pancreas and kidney.
Post Translational Modifications Phosphopantetheinylation at Ser-354 by AASDHPPT is required for the formyltetrahydrofolate dehydrogenase activity.
Function Cytosolic 10-formyltetrahydrofolate dehydrogenase that catalyzes the NADP(+)-dependent conversion of 10-formyltetrahydrofolate to tetrahydrofolate and carbon dioxide. May also have an NADP(+)-dependent aldehyde dehydrogenase activity towards formaldehyde, acetaldehyde, propionaldehyde, and benzaldehyde.
Protein Name Cytosolic 10-Formyltetrahydrofolate Dehydrogenase
10-Fthfdh
Fdh
Aldehyde Dehydrogenase Family 1 Member L1
Database Links Reactome: R-HSA-196757
Cellular Localisation Cytoplasm
Cytosol
Alternative Antibody Names Anti-Cytosolic 10-Formyltetrahydrofolate Dehydrogenase antibody
Anti-10-Fthfdh antibody
Anti-Fdh antibody
Anti-Aldehyde Dehydrogenase Family 1 Member L1 antibody
Anti-ALDH1L1 antibody
Anti-FTHFD antibody

Information sourced from Uniprot.org

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